Centuries later in 1930's America, a certain federal investigator tries his best to combat the rise of organized crime during Prohibition, send a particularly infuriating terrorist to Alcatraz, and catch an outrageous thief duo. Meanwhile, the transcontinental train, the Flying Pussyfoot, begins its trail of blood across the country.
In 2002, a small group of the original Advenna Avis alchemists are on a journey to find the rest of their fellow immortals. However, there is one companion they did not expect to meet again.
Seemingly unrelated events, from a sleepy Italian city in the early 1700's to a modern luxury cruise ship traveling across the Pacific, reveal themselves to be far more connected than anyone could imagine...