The son of a renowned pianist, Shinichi Chiaki, is a devoted and ambitious conductor who is currently in his fourth year at Momogaoka College of Music. While his father's influence was the driving force behind his love for music, his fear of flying has confined him to Japan.
One evening, Chiaki passes out and comes to in the care of his neighbor, Megumi "Nodame" Noda, a peculiar and messy pianist. Initially hesitant to collaborate with Nodame, Chiaki discovers himself enamored with her unique personality - reigniting his passion for music.
What does the future hold for this unexpected musical duo?